148 research outputs found

    Frequency identification of Wiener systems with Backlash operators using separable least squares estimators

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    This paper deals with the identification of Wiener models that involve backlash operators bordered by possibly noninvertible parametric lines. The latter are also allowed to cross each other making possible to account for general-shape static nonlinearities. The linear dynamic subsystem is not-necessarily parametric but is BIBO stable. A frequency identification method is developed that provides estimates of the nonlinear operator parameters as well as estimates of the linear subsystem frequency gain. The method involves standard and separable least squares estimators that all are shown to be consistent. Backlash operators and memoryless nonlinearities are handled within a unified framework.Preprin

    Les corps étrangers en ORL: expérience de dix ans

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    Les corps étrangers (CE) représentent une pathologie fréquemment rencontrée en pratique ORL d'urgence. Ils peuvent constituer une urgence vitale par leur aspect ou leur siÚge. Nous présentons le bilan de dix ans sur la prise en charge des CE de la sphÚre ORL avec une revue de la  littérature. Il s'agit d'une étude rétrospective entre Janvier 2004 et Décembre 2013, incluant tous les cas de CE des voies aéro-digestives supérieures et auriculaires colligés dans le service d'ORL au CHU Mohammed VI de Marrakech au Maroc. Sur les 1317 cas de CE de la sphÚre ORL colligés durant cette période, 80,48% concernaient les enfants. Le sex-ratio était de 1,5. L'ùge moyen était de 12,92 ans. Les CE oesophagiens étaient les plus fréquents (47,53%). Les complications ont été rencontrées dans 11,69% des cas. Les CE dans la sphÚre ORL restent fréquents en pratique quotidienne surtout chez les enfants. Leur prise en charge nécessite une intervention rapide avec un matériel adapté et des médecins entrainés. La prévention reste la meilleure solution

    Retropharyngeal Abscess in Adults: Five Case Reports and Review of the Literature

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    Retropharyngeal abscesses are rare in adults. They occur mostly in immunocompromised patients or as a foreign body complication. We report 5 cases of retropharyngeal abscess collected in the ENT Department of CHU Mohammed VI of Marrakech, during a two-year period (December 2008 to December 2009). Local trauma by foreign body ingestion was the aetiology in four patients. The presenting symptoms, for all patients, were fever, odynophagia, torticollis, and trismus, and the clinical examination showed bulging of the posterior wall of the oropharynx. The radiography of cervical spine showed prevertebral thickening in all cases, this thickening was associated with an aspect of vertebral lysis of the fourth cervical vertebra in one case. A CT scan was performed in all our cases and showed features of retropharyngeal abscess which was associated, in one case, with spondylodiscitis. The biological assessment found one case of diabetes. The intradermal reaction to the tuberculin was clearly positive in one case. Endobuccal abscess puncture was practiced in 4 cases; only one organism was identified by culture: Staphylococcus aureus treatment was based on triple intravenous antibiotics and anti-Koch's therapy (in one case), and the surgical drainage under general anesthesia was also performed in the case of the diabetes patient which required also the correction of hyperglycemia in intensive care unit. The outcome was good in all our patients. The diagnosis of retropharyngeal abscess can be difficult and one must seek a comorbidity; a tuberculosis aetiology must be considered in countries with a high prevalence. The management of these cases is based on antibiotics and surgical drainage

    Identification and Characterization of an Activating F229V Substitution in the V2 Vasopressin Receptor in an Infant with NSIAD

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    Gain-of-function mutations in the gene encoding the V2 vasopressin receptor (V2R) cause nephrogenic syndrome of inappropriate antidiuresis. To date, reported mutations lead to the substitution of arginine 137 by either a cysteine or leucine (R137C/L). Here, we describe a 3-month-old hyponatremic infant found to have a phenylalanine 229 to valine (F229V) substitution in V2R. Characterization of this substitution in vitro revealed that it leads to high constitutive activity of the receptor, compatible with spontaneous antidiuresis. In contrast to R137C/L mutant receptors, F229V receptors do not undergo spontaneous desensitization, which results in sustained, high basal activity. Notably, the V2R-selective inverse agonists tolvaptan and satavaptan completely silenced the constitutive signaling activity of the F229V mutant receptor, indicating that this substitution does not lock the receptor in an irreversible active state. Thus, inverse agonists might prove to be effective therapies for treating patients with this or other spontaneously activating mutations that do not lock the V2R in its active state. These results emphasize the importance of genetic testing and the functional characterization of mutant receptors for patients with nephrogenic syndrome of inappropriate antidiuresis because the results might inform treatment decisions

    Sélection in vitro de lignées de cals de porte-greffes d'agrumes tolérant la salinité

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    Les cals de deux porte-greffes d’agrumes Poncirus trifoliata et Citrus aurantium, induits en prĂ©sence de 2,4-D, ont Ă©tĂ© mis en culture et subit des subcultures successives dans un milieu MS modifiĂ© additionnĂ© de NaCl dont l’application a Ă©tĂ© progressive. La concentration de sel a affectĂ© de façon notable les paramĂštres de croissance mesurĂ©s (poids frais, poids sec, surface et hauteur). Les concentrations 7 g/l et particuliĂšrement 9 g/l sont les plus sĂ©lectives. L’interaction entre la concentration de sel et le gĂ©notype est significative aprĂšs trois subcultures successives et Poncirus trifoliata a prĂ©sentĂ© la meilleure croissance des cals. Le criblage, in vitro, des cals dans les conditions de stress salin a permis ainsi de sĂ©lectionner des lignĂ©es de cals de Poncirus trifoliata tolĂ©rants ayant mĂȘme dĂ©veloppĂ© des pousses feuillĂ©es (18%) en prĂ©sence de 9 g/l de NaCl. Une diffĂ©rence de comportement in vitro vis-Ă -vis du stress salin entre les cals et les jeunes plantules issues des germinations des deux portegreffes a Ă©tĂ© notĂ©e

    Effet allélopathique de quelques plantes médicinales sur la germination des graines de Phalaris canariensis L. et Lactuca sativa L.

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    L’utilisation d’un herbicide naturel peut rĂ©duire les impacts prĂ©judiciables Ă  l’environnement. Dans ce sens l’allĂ©lopathie est considĂ©rĂ©e comme une technique prometteuse pour la lutte biologique. Cependant, les effets des substances allelopathiques restent peu expĂ©rimentĂ©s dans les conditions du laboratoire et du champ. Dans cette Ă©tude, les extraits aqueux des feuilles de 15 espĂšces de diffĂ©rentes rĂ©gions du Maroc ont Ă©tĂ© testĂ©s sur la germination de l’alpiste des canaries (Phalaris canariensis L.) comme plante reprĂ©sentative de la classe des monocotylĂ©dones et la laitue (Lactuca sativa L.) reprĂ©sentative des dicotylĂ©dones. Il s’est avĂ©rĂ© que seules trois espĂšces sur 15 rĂ©pondent aux critĂšres d’un herbicide biologique efficace, il s’agit d’Ammi visnaga (L.) Lam., d’Atractylis gummifera L. et de Ruta montana L.. Ainsi, le taux de rĂ©duction de la germination de l’alpiste des canaries par ces trois plantes variait entre 96 et 100%, alors que la germination de la laitue n’a pas Ă©tĂ© affectĂ©e et dont le pourcentage d’inhibition Ă©tait compris entre -8 et 4%. En effet, les extraits aqueux de ces trois plantes ont montrĂ© une trĂšs bonne efficacitĂ© herbicide sur l’alpiste des canaries et peut ĂȘtre la mĂȘme efficacitĂ© sur les monocotylĂ©dones et une sĂ©lectivitĂ© vis-Ă -vis de la laitue qui serait la mĂȘme pour les dicotylĂ©dones

    Richesse et diversité floristique de la suberaie de la Mamora (Maroc).

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    RÉSUMÉ. Richesse et diversitĂ© floristique de la suberaie de la Mamora (Maroc). L’étude vise la quantification de la richesse et de la diversitĂ© floristique de l’écosystĂšme Ă  chĂȘne - liĂšge de la forĂȘt de la Mamora sur la base de transects et relevĂ©s floristiques rĂ©partis selon un Ă©chantillonnage stratifiĂ© et systĂ©matique dans diffĂ©rentes formations vĂ©gĂ©tales prĂ©alablement distinguĂ©es. Les rĂ©sultats montrent que l’écosystĂšme renferme 62 familles, 261 genres, 408 espĂšces, sous-espĂšces et variĂ©tĂ©s. 35 taxons sont trĂšs rares et 29 rares. 18 taxons sont endĂ©miques, 1 trĂšs rare et endĂ©mique et 4 rares et endĂ©miques. L’étude a, par ailleurs, permis de rĂ©vĂ©ler la disparition totale de Erica arborea et E. scoparia de cet Ă©cosystĂšme et de dĂ©finir le spectre biologique de la rĂ©gion d’étude qui se caractĂ©rise par une nette dominance des thĂ©rophytes (50.5%).Mots clĂ©s. Quercus suber, richesse, diversitĂ©, Mamora, Maroc.ABSTRACT. Floristic richeness and diversity of the Mamora’s Cork Oak forest (Morocco.) The survey aims to quantify the floristic richeness and diversity of the Mamora’s forest oak-cork ecosystem on the basis of transects and floristic samples distributed according to a stratified and systematic sampling in the different plant formations previously distinguished. The results show that the ecosystem contains 62 families, 261 genders, 408 species, subspecies and varieties : 35 very rare taxa , 29 rare taxa ; 18 endemic taxa, 1 very rare and endemic taxa and 4 rare and endemic taxa. The survey has, otherwise, permitted to reveal the total disappearance of Erica arborea and E. scoparia from this ecosystem and to define the biological spectrum of the studied region, wich is characterized with a clear dominance of therophytes (50.5%).Keys words. Quercus suber, richeness, diversity, Mamora, Morocco

    Retropharyngeal Abscess in Adults: Five Case Reports and Review of the Literature

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    Retropharyngeal abscesses are rare in adults. They occur mostly in immunocompromised patients or as a foreign body complication. We report 5 cases of retropharyngeal abscess collected in the ENT Department of CHU Mohammed VI of Marrakech, during a two-year period (December 2008 to December 2009). Local trauma by foreign body ingestion was the aetiology in four patients. The presenting symptoms, for all patients, were fever, odynophagia, torticollis, and trismus, and the clinical examination showed bulging of the posterior wall of the oropharynx. The radiography of cervical spine showed prevertebral thickening in all cases, this thickening was associated with an aspect of vertebral lysis of the fourth cervical vertebra in one case. A CT scan was performed in all our cases and showed features of retropharyngeal abscess which was associated, in one case, with spondylodiscitis. The biological assessment found one case of diabetes. The intradermal reaction to the tuberculin was clearly positive in one case. Endobuccal abscess puncture was practiced in 4 cases; only one organism was identified by culture: Staphylococcus aureus treatment was based on triple intravenous antibiotics and anti-Koch's therapy (in one case), and the surgical drainage under general anesthesia was also performed in the case of the diabetes patient which required also the correction of hyperglycemia in intensive care unit. The outcome was good in all our patients. The diagnosis of retropharyngeal abscess can be difficult and one must seek a comorbidity; a tuberculosis aetiology must be considered in countries with a high prevalence. The management of these cases is based on antibiotics and surgical drainage
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